Ytdyklly

In minute 57:31 of Hotel Artemis the nurse says that her ex-husband moved to Florida and that it alone means he has grown desperate of life or something similar...

Nah. He lives in Florida.
Life took him out already.

Can someone explain why is it said so about Florida?

Florida's warm and a lot of people retire there - so more or less, it's famous for having a lot of elderly out of towners. If he's moved to Florida, it means he's tired of his life where he was.

It's a bit of an old old American joke, and basically means he's retired.

Considering the nurse is a cranky old lady who hasn't retired - sounds like the sort of thing she'd say.

Yup. For most people, when you say someone went to Florida it means they've given up on life. Florida is where you go to die. Especially if you're leaving a big city like New York or Chicago where all the excitement is or if you're leaving your hometown. Florida has warm weather, but it's considered a cultural wasteland, so it's like you don't want excitement and cukture unless it's the stupid beach kind. I'm sorry if you live in Florida.